Case report of mammary analog secretory carcinoma of the parotid gland

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F12%3A10123332" target="_blank" >RIV/00216208:11140/12:10123332 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/j.1440-1827.2011.02759.x" target="_blank" >http://dx.doi.org/10.1111/j.1440-1827.2011.02759.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1440-1827.2011.02759.x" target="_blank" >10.1111/j.1440-1827.2011.02759.x</a>

Result language
angličtina
Original language name
Case report of mammary analog secretory carcinoma of the parotid gland
Original language description
Mammary Analog Secretory Carcinoma (MASC) is a new entity of malignant salivary gland tumors that morphologically resembles mammary secretory carcinoma and carries the identical ETV6-NTRK3 fusion gene. We report our first case of MASC in Japan occurringin the parotid gland of a 37-year-old female patient with a t (12; 15) (p13; q25) translocation. Histologically, the tumor was composed of monomorphic cuboidal cells with low-grade vesicular nuclei and pale eosinophilic cytoplasm, and formed microcysticand tubular spaces with periodic acid-Schiff-positive secretion. Immunohistochemically, the tumor cells tested positive for cytokeratin, vimentin, and S-100 protein. MASC is a morphological mimicker of acinic cell carcinoma, but is a distinct neoplasm characterized by a specific chromosomal translocation. An accumulation of similar case studies is mandatory in order to clarify biological behaviors.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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