Chromophobe renal cell carcinoma - chromosomal aberration variability and its relation to Paner grading system: an array CGH and FISH analysis of 37 cases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F13%3A10144139" target="_blank" >RIV/00216208:11140/13:10144139 - isvavai.cz</a>
Result on the web
<a href="http://download.springer.com/static/pdf/208/art%253A10.1007%252Fs00428-013-1457-6.pdf?auth66=1385022674_00330552c54391337ac47cee6856836b&ext=.pdf" target="_blank" >http://download.springer.com/static/pdf/208/art%253A10.1007%252Fs00428-013-1457-6.pdf?auth66=1385022674_00330552c54391337ac47cee6856836b&ext=.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00428-013-1457-6" target="_blank" >10.1007/s00428-013-1457-6</a>
Alternative languages
Result language
angličtina
Original language name
Chromophobe renal cell carcinoma - chromosomal aberration variability and its relation to Paner grading system: an array CGH and FISH analysis of 37 cases
Original language description
Genetically, chromophobe renal cell carcinoma (ChRCC) is characterized by multiple chromosomal changes, especially losses. The most common losses include chromosomes 1, 2, 6, 10, 13, 17, and 21. The Fuhrman grading system lacks prognostic relevance for ChRCC, and recently, a new grading system for ChRCC was proposed by Paner. The objective of this study was to map the spectrum of chromosomal aberrations (extent and location) in a large cohort of ChRCCs and relate these findings to the Paner grading system (PGS). A large cohort of ChRCC was reviewed and graded according to the PGS. All the cases were reevaluated and separated into groups according to their PGS. The final study set was 37 patients. ChRCCs were divided into PG 1-3, sarcomatoid, and aggressive groups. "Aggressive ChRCCs" were designated cases with known metastatic activity, local recurrence, aggressive growth to the adjacent organs, or invasive growth into the renal sinus (with/without angioinvasion). Sarcomatoid tumors we
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedical Centre of the Faculty of Medicine in Pilsen</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Virchows Archiv : an international journal of pathology
ISSN
0945-6317
e-ISSN
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Volume of the periodical
463
Issue of the periodical within the volume
4
Country of publishing house
DE - GERMANY
Number of pages
11
Pages from-to
563-573
UT code for WoS article
000325392300009
EID of the result in the Scopus database
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