Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10210629" target="_blank" >RIV/00216208:11140/14:10210629 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/14:10210629
Result on the web
<a href="http://dx.doi.org/10.1111/dth.12126" target="_blank" >http://dx.doi.org/10.1111/dth.12126</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/dth.12126" target="_blank" >10.1111/dth.12126</a>

Result language
angličtina
Original language name
Management of a Pemphigus with IgA and IgG antibodies and coexistent lung cancer
Original language description
Immunoglobulin A (IgA) pemphigus is a clinically distinct variant of penphigus characterized by intercellular IgA deposition in the epidermis. Recently, an IgA/Immunoglobulin G (IgG) subset of penphigus with IgA and IgG anti-keratinocyte cell surface antibodies has been described. Both IgA and IgA(IgG penphigus have been associated with internal malignancies. Above all, monoclonal IgA gammopathy in patients with IgA penphigus has been reported, and lung cancers in association with IgA/IgG pemphigus havebeen described. IgA pepnpihus can be successfully treated with dapsone, whereas therapeutic management of IgG/igA pemphigus is not well established yet. We report a rare case of a patient, who developed atypical pemphigus with both IgA and IgG autoantibodies and an underlying lung cancer, successfully treated with corticosteroids and dapsone.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FO - Dermatology and venereology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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