The association of factor V Leiden with various clinical patterns of venous thromboembolism-the factor V Leiden paradox

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10282713" target="_blank" >RIV/00216208:11140/14:10282713 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/14:10282713
Result on the web
<a href="http://dx.doi.org/10.1093/qjmed/hcu055" target="_blank" >http://dx.doi.org/10.1093/qjmed/hcu055</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/qjmed/hcu055" target="_blank" >10.1093/qjmed/hcu055</a>

Result language
angličtina
Original language name
The association of factor V Leiden with various clinical patterns of venous thromboembolism-the factor V Leiden paradox
Original language description
Background: Factor V Leiden (FVL) supposedly carries relatively higher risk of deep vein thrombosis (DVT), compared to the risk of pulmonary embolism (PE). Aim: To prove this paradox in a group of patients with various clinical presentation of venous thromboembolism (VTE). Materials and methods: We retrospectively evaluated clinical pattern of VTE in patients who had been referred to vascular clinic shortly after an acute VTE event. In FVL positive and FVL negative groups we compared the prevalence of isolated symptomatic DVT (proximal or distal) and symptomatic PE with/without DVT, and, moreover, asymptomatic DVT or PE. Results: Of 575 patients (mean age 57 years, 50.1% women), 120 were FVL positive and those had significantly higher prevalence of isolated symptomatic DVT, compared to symptomatic PE with/without DVT. Proximal DVT location was significantly more frequent in FVL carriers. The prevalence of asymptomatic PE did not differ between the two groups. The rate of asymptomatic D
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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