Bronchial inflammation in seasonal allergic rhinitis with or without asthma in relation to natural exposure to pollen allergens

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10143954" target="_blank" >RIV/00216208:11140/15:10143954 - isvavai.cz</a>

Alternative codes found

RIV/75010330:_____/15:00010134

Result on the web

<a href="http://dx.doi.org/10.1016/j.aller.2013.06.009" target="_blank" >http://dx.doi.org/10.1016/j.aller.2013.06.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.aller.2013.06.009" target="_blank" >10.1016/j.aller.2013.06.009</a>

Result language

angličtina

Original language name

Bronchial inflammation in seasonal allergic rhinitis with or without asthma in relation to natural exposure to pollen allergens

Original language description

Background Nasal inflammation in allergic rhinitis enhances bronchial Th2 driven inflammation and development of asthma. We assessed bronchial inflammation induced by natural allergen exposure during pollen season in patients with pollinosis with or without asthma to show the intensity of inflammation in asthma and rhinitis and possible persistence of inflammation in periods without allergen exposure. Methods Sputum was induced in 52 patients with seasonal allergic rhinitis without asthma, 38 patients with seasonal allergic rhinitis and seasonal asthma and 23 healthy volunteers. Sampling was performed 6-8 weeks before the expected beginning of symptoms, during symptomatic period and 6-8 weeks after the end of symptoms. Sputum ECP was measured by meansof chemiluminiscent immunometric assay and sputum cell counts were assessed by classical staining and immunocytochemistry. Results Sputum eosinophils were on the whole higher in both asthma and rhinitis compared to controls (p < 0.001, p

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Allergologia et Immunopathologia

ISSN

0301-0546

e-ISSN

—

Volume of the periodical

43

Issue of the periodical within the volume

1

Country of publishing house

ES - SPAIN

Number of pages

7

Pages from-to

3-9

UT code for WoS article

000349067400001

EID of the result in the Scopus database

2-s2.0-84921540364