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Mammary analogue secretory carcinoma of salivary glands: a new entity associated with ETV6 gene rearrangement

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10293644" target="_blank" >RIV/00216208:11140/15:10293644 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s00428-014-1701-8" target="_blank" >http://dx.doi.org/10.1007/s00428-014-1701-8</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00428-014-1701-8" target="_blank" >10.1007/s00428-014-1701-8</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mammary analogue secretory carcinoma of salivary glands: a new entity associated with ETV6 gene rearrangement

  • Original language description

    Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumour that harbours the recurrent ETV6-NTRK3 translocation. This is the first series of MASC cases identified in the historic cohort of carcinomas of salivary glands withclinical/pathological correlation and follow-up data. We reviewed 183 primary carcinomas of major and minor salivary glands resected at the Medical University of Gdańsk, Poland, between 1992 and 2012. Based on morphology and immunohistochemistry, casessuspiciou for MASC were selected, and the diagnosis was confirmed by fluorescence in situ hybridization (FISH) for ETV6 rearrangement and by RT-PCR for the ETV6-NTRK3 fusion transcript. Seven carcinomasmet the criteria ofMASC, as they exhibited a typicalappearance with solid/microcystic and papillary architecture and intraluminal secretions, and cells completely evoid of basophilic cytoplasmic zymogen granules indicative f true acinar differentiation. The only paediatric case was n unen

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Virchows Archiv : an international journal of pathology

  • ISSN

    0945-6317

  • e-ISSN

  • Volume of the periodical

    466

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    245-254

  • UT code for WoS article

    000351145000002

  • EID of the result in the Scopus database

    2-s2.0-84925519941