Mammary analogue secretory carcinoma of salivary glands: a new entity associated with ETV6 gene rearrangement
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10293644" target="_blank" >RIV/00216208:11140/15:10293644 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00428-014-1701-8" target="_blank" >http://dx.doi.org/10.1007/s00428-014-1701-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00428-014-1701-8" target="_blank" >10.1007/s00428-014-1701-8</a>
Alternative languages
Result language
angličtina
Original language name
Mammary analogue secretory carcinoma of salivary glands: a new entity associated with ETV6 gene rearrangement
Original language description
Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumour that harbours the recurrent ETV6-NTRK3 translocation. This is the first series of MASC cases identified in the historic cohort of carcinomas of salivary glands withclinical/pathological correlation and follow-up data. We reviewed 183 primary carcinomas of major and minor salivary glands resected at the Medical University of Gdańsk, Poland, between 1992 and 2012. Based on morphology and immunohistochemistry, casessuspiciou for MASC were selected, and the diagnosis was confirmed by fluorescence in situ hybridization (FISH) for ETV6 rearrangement and by RT-PCR for the ETV6-NTRK3 fusion transcript. Seven carcinomasmet the criteria ofMASC, as they exhibited a typicalappearance with solid/microcystic and papillary architecture and intraluminal secretions, and cells completely evoid of basophilic cytoplasmic zymogen granules indicative f true acinar differentiation. The only paediatric case was n unen
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Virchows Archiv : an international journal of pathology
ISSN
0945-6317
e-ISSN
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Volume of the periodical
466
Issue of the periodical within the volume
3
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
245-254
UT code for WoS article
000351145000002
EID of the result in the Scopus database
2-s2.0-84925519941