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PHI in the Early Detection of Prostate Cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10295981" target="_blank" >RIV/00216208:11140/15:10295981 - isvavai.cz</a>

  • Alternative codes found

    RIV/00669806:_____/15:10295981

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    PHI in the Early Detection of Prostate Cancer

  • Original language description

    To evaluate changes in the serum levels of prostate specific antigen (PSA), %free PSA and -2proPSA biomarkers, and prostate health index (PHI) in the diagnostic algorithm of early prostate cancer. Patients and Methods: The Immunoanalytical Laboratory ofthe University Hospital in Pilsen examined sera from 263 patients being treated at the Hospital's Urology Department with suspected prostate cancer who had undergone biopsies and were divided into a benign and malignant group. The monitored biomarkers were measured using chemiluminescence. All statistical analyses were calculated using the SAS software. Results: We found statistically significantly increased levels of -2proPSA, PHI and PSA and decreased levels of %freePSA in patients diagnosed with prostate cancer by prostate biopsy vs. patients with benign prostatic hypertrophy (median values: -2proPSA: 16 vs. 21 ng/l, PHI: 35 vs. 62, total PSA: 7.2 vs. 7.7 mu g/l and % free PSA: 16.7 vs. 11.7%). Receiver operating characteristic curve

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/EE2.3.20.0040" target="_blank" >EE2.3.20.0040: Molecular genetics of tumor and cardiovascular diseases</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Anticancer Research

  • ISSN

    0250-7005

  • e-ISSN

  • Volume of the periodical

    35

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    GR - GREECE

  • Number of pages

    3

  • Pages from-to

    4855-4857

  • UT code for WoS article

    000359311000036

  • EID of the result in the Scopus database

    2-s2.0-84939645623