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Relevance of low viral load in haemodialysed patients with chronic hepatitis C virus infection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10311892" target="_blank" >RIV/00216208:11140/15:10311892 - isvavai.cz</a>

  • Alternative codes found

    RIV/00669806:_____/15:10311892 RIV/00023001:_____/15:00059425

  • Result on the web

    <a href="http://dx.doi.org/10.3748/wjg.v21.i18.5496" target="_blank" >http://dx.doi.org/10.3748/wjg.v21.i18.5496</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3748/wjg.v21.i18.5496" target="_blank" >10.3748/wjg.v21.i18.5496</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Relevance of low viral load in haemodialysed patients with chronic hepatitis C virus infection

  • Original language description

    AIM: To identify predictors of sustained virological response in hemodialysed patients treated by PEGinterferon alpha for chronic hepatitis C, genotype 1. METHODS: The sustained virological response (SVR) rate, IL28B genotype, IFNL4 genotype, initial viral load (IVL) and other pretreatment variables in 39 end-stage renal disease patients (ESRD) on maintenance haemodialysis (HD) infected with hepatitis C virus (HCV), genotype 1b, were compared with a control group of 109 patients with normal kidney function treated within the same period. All the patients were treatment naive and had well compensated liver disease. The ESRD patients received 135 mu g of PEGylated interferon alpha-2a (PegIFN-alpha) weekly and a reduced dose of ribavirin (RBV) was administered to 23/39 patients with an initial haemoglobin level > 10 g/dL. Control group patients were given standard doses of PegIFN-alpha and RBV. SVR was assessed as hcv RNA negativity 24 wk post-treatment. A t-test or ANOVA were used for co

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT11235" target="_blank" >NT11235: Role of the host-dependent factors in prediction of antiviral treatment response in chronic hepatitis C</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    World Journal of Gastroenterology

  • ISSN

    1007-9327

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    18

  • Country of publishing house

    CN - CHINA

  • Number of pages

    9

  • Pages from-to

    5496-5504

  • UT code for WoS article

    000354800200007

  • EID of the result in the Scopus database

    2-s2.0-84929166244