Cervical Lymph node metastasis in high-grade transformation of head and neck adenoid cystic carcinoma: a collective international review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10322794" target="_blank" >RIV/00216208:11140/16:10322794 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s12325-016-0298-5" target="_blank" >http://dx.doi.org/10.1007/s12325-016-0298-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12325-016-0298-5" target="_blank" >10.1007/s12325-016-0298-5</a>
Alternative languages
Result language
angličtina
Original language name
Cervical Lymph node metastasis in high-grade transformation of head and neck adenoid cystic carcinoma: a collective international review
Original language description
Adenoid cystic carcinoma (AdCC) is among the most common malignant tumors of the salivary glands. It is characterized by a prolonged clinical course, with frequent local recurrences, late onset of metastases and fatal outcome. High-grade transformation (HGT) is an uncommon phenomenon among salivary carcinomas and is associated with increased tumor aggressiveness. In AdCC with high-grade transformation (AdCC-HGT), the clinical course deviates from the natural history of AdCC. It tends to be accelerated, with a high propensity for lymph node metastasis. In order to shed light on this rare event and, in particular, on treatment implications, we undertook this review: searching for all published cases of AdCC-HGT. We conclude that it is mandatory to perform elective neck dissection in patients with AdCC-HGT, due to the high risk of lymph node metastases associated with transformation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advances in Therapy
ISSN
0741-238X
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
357-368
UT code for WoS article
000374258600004
EID of the result in the Scopus database
2-s2.0-84958755163