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Gasotransmitters in gametogenesis and early development: Holy Trinity for Assisted Reproductive Technology. A Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10324444" target="_blank" >RIV/00216208:11140/16:10324444 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1155/2016/1730750" target="_blank" >http://dx.doi.org/10.1155/2016/1730750</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1155/2016/1730750" target="_blank" >10.1155/2016/1730750</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Gasotransmitters in gametogenesis and early development: Holy Trinity for Assisted Reproductive Technology. A Review

  • Original language description

    Creation of both gametes, sperm and oocyte, and their fusion during fertilization, are essential step for beginning of life. Although molecular mechanisms regulating gametogenesis, fertilization and early embryonic development are still subjected to intensive study, a lot of phenomena remains unclear. Based on our best knowledge and own results, we consider gastoransmitters to be esential or various signalisation in oocytes and embryos. In accordance to nitric oxide (NO) and hydrogen sulfide (H2S) physiological necessity, their involvement during oocyte maturation and regulative role in fertilization followed by embryonic development have been described. During these processes, NO- and H2S-derived post-translational modifications represent the main mode of their regulative effect. While NO represent the most understood gasotransmitter and H2S is still intensively studied gasotransmitter, appreciation of carbon monoxide (CO) role in reproduction is still missing. Overall understanding of gasotransmitters including their interaction is promising for reproductive medicine and assisted reproductive technologies (ART), because these approaches contend with failure of in vitro assisted reproduction.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LO1503" target="_blank" >LO1503: BIOMEDIC</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Oxidative Medicine and Cellular Longevity

  • ISSN

    1942-0900

  • e-ISSN

  • Volume of the periodical

    Neuveden

  • Issue of the periodical within the volume

    august

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

  • UT code for WoS article

    000382048000001

  • EID of the result in the Scopus database

    2-s2.0-84984674617