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Infundibulocystic structures and prominent squamous metaplasia in sebaceoma - a rare feature, A clinicopathologic study of 10 cases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10326297" target="_blank" >RIV/00216208:11140/16:10326297 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1097/DAD.0000000000000494" target="_blank" >http://dx.doi.org/10.1097/DAD.0000000000000494</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1097/DAD.0000000000000494" target="_blank" >10.1097/DAD.0000000000000494</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Infundibulocystic structures and prominent squamous metaplasia in sebaceoma - a rare feature, A clinicopathologic study of 10 cases

  • Original language description

    The authors describe 10 cases of sebaceoma that manifested prominent infundibulocystic structures in all cases and, additionally, conspicuous squamous metaplasia in 6 neoplasms. All tumors occurred on the scalp or the face (2 cases lacked clinical information) and presented as a solitary lesion, measuring from 5 to 20 mm. The patients' age ranged from 22 to 89 years. The main component of all tumors was small, uniform basaloid cells (immature sebocytes) intermixed with mature sebocytes clearly arranged in nodules, classifying the lesions as a sebaceoma. In all neoplasms, the tumor cells showed organoid growth patterns of sebaceoma, including rippled, sinusoidal/labyrinthine, and carcinoid-like, occurring alone or in combination. Additionally, numerous infundibulocystic structures were readily noticed and were either distributed multifocally or unilocular within the tumors. In some cases, they were segregated from the main tumor bulk. The authors posit that these structures, which are different from both sebaceous ductal differentiation and squamous metaplasia, represent an authentic follicular differentiation. The infundibulocystic features (combined with squamous metaplasia), when prominent and in a limited biopsy specimen, may cause a confusion with trichoadenoma or even microcystic adnexal carcinoma.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    American Journal of Dermatopathology

  • ISSN

    0193-1091

  • e-ISSN

  • Volume of the periodical

    38

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    678-682

  • UT code for WoS article

    000382251800009

  • EID of the result in the Scopus database

    2-s2.0-84954349670