Neuronal oscillations and memory retrieval

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10364911" target="_blank" >RIV/00216208:11140/17:10364911 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Neuronal oscillations and memory retrieval

Original language description

Brain oscillations, reflecting rhythmic excitation and inhibition of neuronal populations, play essential role in coordination of neuronal activity. Study of rhythmic activity in hippocampus revealed its importance for memory processing. However, memory retrieval, the final stage of memory cascade, remains an elusive phenomenon. Analysis of hippocampal network activity during spatial memory retrieval pointed to significance of theta oscillations, the EEG pattern in hippocampus (5-12 Hz) that dominates during periods of active (&quot;online&quot;) processing of information. Recurrent excitation in CA3 subregion of hippocampus keeps the memory network in a stable attractor state. Periodic inhibition during theta oscillations disrupts attractor dynamics and enables memory recall by transition to corresponding network state. The main source of input to hippocampus is entorhinal cortex, whose medial division is dedicated to spatial position representation, while the lateral part is associated with coding for local sensory stimuli. The communication between entorhinal cortex and hippocampus is coordinated by gamma rhythms (25-100 Hz). Which inputs originating in the entorhinal cortex initiate retrieval of memory for spatial context remains unclear. Further studies with simultaneous recording of activity from various hippocampal sub-regions and associated structures could reveal more about dynamics of memory retrieval and their coordination by neuronal oscillations.

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Plzeňský lékařský sborník

ISSN

0551-1038

e-ISSN

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Volume of the periodical

2017

Issue of the periodical within the volume

83

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

11

Pages from-to

19-29

UT code for WoS article

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EID of the result in the Scopus database

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