Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10365228" target="_blank" >RIV/00216208:11140/18:10365228 - isvavai.cz</a>
Alternative codes found
RIV/49777513:23520/18:43953579 RIV/00669806:_____/18:10365228
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S138824571731146X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S138824571731146X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clinph.2017.10.038" target="_blank" >10.1016/j.clinph.2017.10.038</a>

Result language
angličtina
Original language name
Cognitive impairment measured by event-related potentials during early and late postoperative period following intravenous or inhalation anaesthesia
Original language description
Objective This study investigated modification in cognitive function following inhalation (IA) and total intravenous (TIVA) anaesthesia measured using auditory ERPs (Event Related Potentials). Methods Auditory ERPs examination with N1, P3a and P3b component registration was carried out one day before surgery (D-1) and on the first (D+1), sixth (D+6) and 42nd (D+42) days after surgery. Results were compared between two anaesthetic groups. Results On D+1, N1 latency was increased in the IA group. A significant reduction was observed in amplitude of the P3a component on D+6, which persisted up to D+42 for both IA and TIVA groups. A reduction in the amplitude of P3b on D+1 with normalization by D+6 was found in both groups as well. Conclusions Intravenous and inhalation anaesthesia lead to similar changes in cognitive function as determined by ERPs, both during the early and late postoperative periods. It cannot be clearly confirmed whether the observed effects are due to anaesthesia or other unmonitored perioperative factors. Significance Post anaesthetic changes represent a subclinical impairment; nevertheless, they represent a potential risk for subsequent development of cognitive difficulties.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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