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A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10372467" target="_blank" >RIV/00216208:11140/18:10372467 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1097/DAD.0000000000000970" target="_blank" >http://dx.doi.org/10.1097/DAD.0000000000000970</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1097/DAD.0000000000000970" target="_blank" >10.1097/DAD.0000000000000970</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course

  • Original language description

    Lymphomatoid papulosis (LyP) type E is a recently delineated variant characterized by the occurrence of large necrotic &quot;eschar&quot;-like lesions displaying microscopically angioinvasive and angiodestructive infiltrates composed of CD30+ lymphocytes, frequently coexpressing CD8. In contrast to other LyP variants where patients develop multiple lesions, most patients with LyP type E present with few lesions (often 1 or 2 at a given time). In this article, we describe a 34-year-old man with LyP type E with an exacerbated clinical course characterized by the occurrence of almost a hundred of lesions. Initially, he presented with a single rapidly growing 2-cm large erythematous nodule on the forearm but after the administration of doxycycline multiple eschar-like lesions developed all over the body. Atypical lymphoid infiltrates with marked angiocentricity and angiotropism of CD30+ mediumsized to large pleomorphic lymphocytes were seen histopathologically. After the withdrawal of the antibiotic, the lesions spontaneously regressed. Awareness of this rare LyP variant and its correct recognition, even if the clinical course is unusual and worrisome, is important to avoid aggressive treatment.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30109 - Pathology

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    The American Journal of Dermatopathology

  • ISSN

    0193-1091

  • e-ISSN

  • Volume of the periodical

    40

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    3

  • Pages from-to

    145-147

  • UT code for WoS article

    000441159400015

  • EID of the result in the Scopus database

    2-s2.0-85048362399