A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10372467" target="_blank" >RIV/00216208:11140/18:10372467 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1097/DAD.0000000000000970" target="_blank" >http://dx.doi.org/10.1097/DAD.0000000000000970</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/DAD.0000000000000970" target="_blank" >10.1097/DAD.0000000000000970</a>
Alternative languages
Result language
angličtina
Original language name
A Case of Lymphomatoid Papulosis Type E With an Unusual Exacerbated Clinical Course
Original language description
Lymphomatoid papulosis (LyP) type E is a recently delineated variant characterized by the occurrence of large necrotic "eschar"-like lesions displaying microscopically angioinvasive and angiodestructive infiltrates composed of CD30+ lymphocytes, frequently coexpressing CD8. In contrast to other LyP variants where patients develop multiple lesions, most patients with LyP type E present with few lesions (often 1 or 2 at a given time). In this article, we describe a 34-year-old man with LyP type E with an exacerbated clinical course characterized by the occurrence of almost a hundred of lesions. Initially, he presented with a single rapidly growing 2-cm large erythematous nodule on the forearm but after the administration of doxycycline multiple eschar-like lesions developed all over the body. Atypical lymphoid infiltrates with marked angiocentricity and angiotropism of CD30+ mediumsized to large pleomorphic lymphocytes were seen histopathologically. After the withdrawal of the antibiotic, the lesions spontaneously regressed. Awareness of this rare LyP variant and its correct recognition, even if the clinical course is unusual and worrisome, is important to avoid aggressive treatment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The American Journal of Dermatopathology
ISSN
0193-1091
e-ISSN
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Volume of the periodical
40
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
3
Pages from-to
145-147
UT code for WoS article
000441159400015
EID of the result in the Scopus database
2-s2.0-85048362399