A more sensitive detection of micrometastases of NSCLC in lymph nodes using the one-step nucleic acid amplification (OSNA) method
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10373784" target="_blank" >RIV/00216208:11140/18:10373784 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/18:10373784
Result on the web
<a href="https://doi.org/10.1002/jso.24826" target="_blank" >https://doi.org/10.1002/jso.24826</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jso.24826" target="_blank" >10.1002/jso.24826</a>
Alternative languages
Result language
angličtina
Original language name
A more sensitive detection of micrometastases of NSCLC in lymph nodes using the one-step nucleic acid amplification (OSNA) method
Original language description
Detection of tumor cells in lymph nodes (LNs) removed during the Treatment of pulmonary tumor by radical surgery is limited by the possibilities of standart histopathological methods. The goal of this study was to obtain more accureate pTNM status by a more sensitive detection of micrometastases in LNs. Results: identical results for H&E and OSNA examinations were recorded in 286 groups of LNs (89,4%). In total, positive examinations were recorded in 27 groups of LNs (8,4%) using the OSNA method, which were H&E negative. In 7 groups of LNs (2,2%), the H&E examination was positive, while OSNA method produced negative results. Conclusions: the OSNA examination led to a higher pTNM stage classification in 14 (21,9%) patients. The clinical significance remains the subject of follow-up research.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30212 - Surgery
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Surgical Oncology
ISSN
0022-4790
e-ISSN
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Volume of the periodical
117
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
163-170
UT code for WoS article
000426165700008
EID of the result in the Scopus database
2-s2.0-85038258405