Mycosis fungoides manifesting as giant cell lichenoid dermatitis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10377213" target="_blank" >RIV/00216208:11140/18:10377213 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1097/DAD.0000000000001032" target="_blank" >http://dx.doi.org/10.1097/DAD.0000000000001032</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/DAD.0000000000001032" target="_blank" >10.1097/DAD.0000000000001032</a>

Result language

angličtina

Original language name

Mycosis fungoides manifesting as giant cell lichenoid dermatitis

Original language description

Mycosis fungoides (MF) is the most common form of primary cutaneous lymphoma with a broad clinicopathological spectrum. Unusual histopathologic patterns of MF include lichenoid, interstitial, folliculotropic, spongiotic, granulomatous, and many others. Several cases of unusual lichenoid reaction characterized by a mixed lichenoid inflammatory infiltrate with prominent infiltration of the papillary dermis and epidermis by multinucleated giant cells were described under the name of &quot;giant cell lichenoid dermatitis,&quot; most of them were considered to represent a drug eruption. Herein, we describe a 77-year-old woman with a 5-year history of MF displaying microscopic features of giant cell lichenoid dermatitis. Histology revealed a dense band-like lichenoid epidermotropic infiltrate composed of CD4 small to medium-sized lymphocytes with cerebriform nuclei with the presence of multinucleated giant cells in the papillary dermis, within the epidermis, and some hair follicles. Monoclonal TCR gene rearrangement was detected using PCR. To the best of our knowledge, this pattern was never described in MF.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30109 - Pathology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The American Journal of Dermatopathology

ISSN

0193-1091

e-ISSN

—

Volume of the periodical

40

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

3

Pages from-to

283-285

UT code for WoS article

000441163200015

EID of the result in the Scopus database

2-s2.0-85052559517