Endocrine Disruptors: Very Low Doses with Genuinely High Impacts on Male Reproduction
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F20%3A10404748" target="_blank" >RIV/00216208:11140/20:10404748 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/20:00072877 RIV/00216224:14110/20:00118068
Result on the web
<a href="http://dx.doi.org/10.5772/intechopen.88142" target="_blank" >http://dx.doi.org/10.5772/intechopen.88142</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5772/intechopen.88142" target="_blank" >10.5772/intechopen.88142</a>
Alternative languages
Result language
angličtina
Original language name
Endocrine Disruptors: Very Low Doses with Genuinely High Impacts on Male Reproduction
Original language description
Endocrine disruptors (EDs) are chemical substances that affect physiological processes in the body via hormonal regulation. They are often detected in food, plastic water bottles, cosmetics, and many other daily need items. Thereafter, EDs are detected in many bodily fluids, pointing out the real exposure to even very low doses. Permanent and long-term utilization of EDs has harmful effects on male reproductive health mainly due to interference with sex hormone synthesis and mechanism of action. However, with decreasing dosage of EDs, the possibilities of unpredictable modes of action arise. In addition to various molecular actions of individual EDs, the interference of individual ones represents another dimension of the ED issue. This review provides an overview of the EDs and their possible impact on reproductive health in males, with focus on sperm quality with the mighty potential of epigenetic transmission to further generations. The "posttranslational" effect of EDs in really low doses in real exposure routes is stigmatized in this review, being strongly considered as creeping molecular action of individual EDs as well as amplifications of their copresence in the environment.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30105 - Physiology (including cytology)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Male Reproductive Health
ISBN
978-1-78985-648-4
Number of pages of the result
21
Pages from-to
1-21
Number of pages of the book
202
Publisher name
IntechOpen
Place of publication
London
UT code for WoS chapter
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