Histologic Considerations and Salivary Gland Tumor Classification in Surgical Pathology
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F23%3A10478821" target="_blank" >RIV/00216208:11140/23:10478821 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-3-031-26662-1_11" target="_blank" >https://doi.org/10.1007/978-3-031-26662-1_11</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-26662-1_11" target="_blank" >10.1007/978-3-031-26662-1_11</a>
Alternative languages
Result language
angličtina
Original language name
Histologic Considerations and Salivary Gland Tumor Classification in Surgical Pathology
Original language description
The classification of salivary gland neoplasms is dynamic and continues to evolve as reflected in the 2022 fifth edition World Health Organization (WHO) Classification of Head and Neck Tumours. A significant contributor to the evolution in the classification of salivary gland tumors is the utilization of molecular testing in their diagnosis and differential diagnosis. Since the fourth edition of the WHO Classification more salivary gland tumors have been shown to harbor tumor type-specific rearrangements resulting in the identification of new types of salivary gland tumors or a delineation of specific subtypes within previously established tumor types. In addition to the tumor types with previously defining molecular alterations including pleomorphic adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma, secretory carcinoma, hyalinizing clear cell carcinoma, epithelial-myoepithelial carcinoma, and myoepithelial carcinoma, more recently molecularly defined tumor types include intraductal carcinoma, microsecretory carcinoma, and mucinous adenocarcinoma. Undoubtedly, molecular testing has significantly contributed to the advances in the diagnosis of salivary gland tumors but the basis in the evaluation of all salivary gland lesions remains their histology supported by immunohistochemical features. This fact is reflected in the WHO classification which is a morphologic-based classification separating neoplastic entities primarily on tumor morphology to predict their biological behavior, albeit buttressed by immunohistochemical staining and molecular testing.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
The Milan System for Reporting Salivary Gland Cytopathology
ISBN
978-3-031-26661-4
Number of pages of the result
7
Pages from-to
229-235
Number of pages of the book
240
Publisher name
Springer
Place of publication
Cham
UT code for WoS chapter
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