Direct identification of OXA-48-type carbapenemases by detection of β-lactone specific signal using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F24%3A10478549" target="_blank" >RIV/00216208:11140/24:10478549 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=6uRh2j-P3V" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=6uRh2j-P3V</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijantimicag.2024.107130" target="_blank" >10.1016/j.ijantimicag.2024.107130</a>

Result language
angličtina
Original language name
Direct identification of OXA-48-type carbapenemases by detection of β-lactone specific signal using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry
Original language description
The results of this study confirm our hypothesis that the β- lactone-corresponding signal is specific for OXA-48-type carbapen- emases and can be used for identification of these enzymes using MALDI-TOF MS-based meropenem degradation assay. This finding enables us to update an algorithm for carbapenemase detection by MALDI-TOF MS.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30303 - Infectious Diseases

Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)