Oncocytic intraductal carcinoma of parotid gland with a novel AGK::BRAF gene fusion

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F24%3A10485213" target="_blank" >RIV/00216208:11140/24:10485213 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=4hHGd61.Jq" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=4hHGd61.Jq</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00428-024-03928-z" target="_blank" >10.1007/s00428-024-03928-z</a>

Result language
angličtina
Original language name
Oncocytic intraductal carcinoma of parotid gland with a novel AGK::BRAF gene fusion
Original language description
Intraductal carcinoma (IDC) is a rare salivary gland malignancy with four subtypes having morphological and molecular differences. This study presents a novel gene fusion in oncocytic IDC of parotid gland of a 67-year-old male. Consistent with oncocytic IDC, the resection specimen revealed an intraductal cystic neoplasia with papillary epithelial fronds and oncocytic cellular features, surrounded by p63 positive myoepithelial cells. Additionally, S100/SOX10 and mammaglobin were positive but androgen receptor was negative. Next generation sequencing disclosed a novel fusion AGK::BRAF.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30109 - Pathology

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)