Effect of irinotecan on phenotype of peripheral blood leukocyte populations in patients metastatic colorectal cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F02%3A00001072" target="_blank" >RIV/00216208:11150/02:00001072 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of irinotecan on phenotype of peripheral blood leukocyte populations in patients metastatic colorectal cancer
Original language description
CD3+CD4+lymphocytopenia, a decrease in CD8+CD28+ and CD19+lymphocytes, increased expression of activation markers and CD14+CD16+monocytosis are present in a significant proportion of metastatic colorectal cancer patients. CPT-11-based therapy seems to ameliorate CD3+CD4+lymphocytopenia, possibly by neutralizing the immunosuppressive effects of uncontrolled tumor growth. These observation may be useful for the design of immunotherapy trials in metastatic colorectal cancer.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Hepato-Gastroenterology
ISSN
0172-6390
e-ISSN
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Volume of the periodical
46
Issue of the periodical within the volume
49
Country of publishing house
DE - GERMANY
Number of pages
3
Pages from-to
967-970
UT code for WoS article
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EID of the result in the Scopus database
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