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Proliferation and differentiation of adult endogenous neural stem cells in response to neurodegenerative process in the striatum

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F06%3A00004014" target="_blank" >RIV/00216208:11150/06:00004014 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Proliferation and differentiation of adult endogenous neural stem cells in response to neurodegenerative process in the striatum

  • Original language description

    In an animal model of Huntington's disease, the neurodegenerative process in the striatum initiates intensive cell proliferation and differentiation resulting in characteristic enlargement of the SEZ in damaged hemisphere. The important changes in neurogenic niche, based on immunoflurescence detection mainly of the sequence of glial intermediate filaments, are described.

  • Czech name

    Proliferace a diferenciace adultních endogenních neurálních kmenových buněk v odpovědi na neurodegenerativní proces ve striatu

  • Czech description

    U modelu Huntingtonovy choroby vyvolává neurodegenerativní proces ve striatu intenzivní proliferaci a diferenciaci buněk, vedoucí k charakteristickému rozšíření SEZ v poškozené hemisféře. V práci jsou popsány významné změny v neurogenním niché, založenéna imunofluorescenční detekci zejména sekvence gliových intermediálních filament.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NF7594" target="_blank" >NF7594: The experimental model of Huntington's disease: The reaction of the subependymal layer of lateral ventricles to neurodegenerative process within the striatum, and to the fetal neural graft.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neurodegenerative Diseases

  • ISSN

    1660-2854

  • e-ISSN

  • Volume of the periodical

    3

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    7

  • Pages from-to

    12-18

  • UT code for WoS article

  • EID of the result in the Scopus database