Effect of galanthamine on acetylcholinesterase and butyrylcholinsterase activities in the presence of L-carnitine in rat selected brain and peripheral tissues
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F06%3A00004110" target="_blank" >RIV/00216208:11150/06:00004110 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of galanthamine on acetylcholinesterase and butyrylcholinsterase activities in the presence of L-carnitine in rat selected brain and peripheral tissues
Original language description
We attempted to achieve pharmacologically-induced enhancement of the parasympathomimetic activity of galanthamine in the key areas of rat brain, using an interactive combination of the alkaloid with the transmembrane enhancer L-carnitine. Carnitine in terms of positive modulation of galanthamine targeting to the central nervous system had no significant effect.
Czech name
Vliv galantaminu na aktivitu acetylcholinnesterasy a butyrylcholinesterasy ve vybraných částech mozku a periferních tkáních v přítomnosti L-karnitinu
Czech description
Sledovali jsme možné zesílení parasympatické aktivity galantaminu v klíčových oblastech mozku potkana pomocí transmembránového enhanceru L-karnitinu. Studie v tomto smyslu neprokázala statisticky signifikantní modulaci účinku galantaminu v synergii s L-karnitinem.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NR7935" target="_blank" >NR7935: Interactions of galanthamine with modulators of membrane transport in the central nervous system</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroendocrinology Letters
ISSN
0172-780X
e-ISSN
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Volume of the periodical
27
Issue of the periodical within the volume
Suppl. 2
Country of publishing house
SE - SWEDEN
Number of pages
4
Pages from-to
183-186
UT code for WoS article
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EID of the result in the Scopus database
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