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Effect of collagen type I gel and fibrin gel cultivation on gene expression in liver myofibroblasts

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F07%3A00003699" target="_blank" >RIV/00216208:11150/07:00003699 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of collagen type I gel and fibrin gel cultivation on gene expression in liver myofibroblasts

  • Original language description

    In the present study we investigated the influence of extracellular matrix components (fibrin and collagen gel) on gene expression in rat liver myofibroblasts (MFB). cDNA array analysis showed changes in the expression of a number genes in MFB cultivatedin gels when compared to MFB cultivated on plastic. The results were confirmed by rt RT-PCR. We can conclude that both fibrin and collagen type I influenced the expression of some genes involved in connective tissues remodelling.

  • Czech name

    Vliv kultivace v kolagenním a fibrinovém gelu na genovou expresi jaterních myofibroblastů

  • Czech description

    V naší práci se zabýváme vlivem kolagenního a fibrinového gelu na jaterní myofibroblasty. Výsledky cDNA arrayí, potvrzené pomocí rt RT-PCR ukázaly změny v expresi řady genů důležitých pro remodelaci jaterní pojivové tkáně.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    New Frontiers in the Research of PhD Students: The 4th International Conference of Postgraduate Medical Students

  • ISBN

    978-80-254-0839-1

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    56-58

  • Publisher name

    UK. LFHK

  • Place of publication

    Hradec Králové

  • Event location

  • Event date

  • Type of event by nationality

  • UT code for WoS article