Effect of collagen type I gel and fibrin gel cultivation on gene expression in liver myofibroblasts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F07%3A00003699" target="_blank" >RIV/00216208:11150/07:00003699 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of collagen type I gel and fibrin gel cultivation on gene expression in liver myofibroblasts
Original language description
In the present study we investigated the influence of extracellular matrix components (fibrin and collagen gel) on gene expression in rat liver myofibroblasts (MFB). cDNA array analysis showed changes in the expression of a number genes in MFB cultivatedin gels when compared to MFB cultivated on plastic. The results were confirmed by rt RT-PCR. We can conclude that both fibrin and collagen type I influenced the expression of some genes involved in connective tissues remodelling.
Czech name
Vliv kultivace v kolagenním a fibrinovém gelu na genovou expresi jaterních myofibroblastů
Czech description
V naší práci se zabýváme vlivem kolagenního a fibrinového gelu na jaterní myofibroblasty. Výsledky cDNA arrayí, potvrzené pomocí rt RT-PCR ukázaly změny v expresi řady genů důležitých pro remodelaci jaterní pojivové tkáně.
Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
New Frontiers in the Research of PhD Students: The 4th International Conference of Postgraduate Medical Students
ISBN
978-80-254-0839-1
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
56-58
Publisher name
UK. LFHK
Place of publication
Hradec Králové
Event location
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Event date
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Type of event by nationality
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UT code for WoS article
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