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The activation of adult endogenous neural stem cells by neurodegenerative process within the striatum in an animal model of Huntington's disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F08%3A00106661" target="_blank" >RIV/00216208:11150/08:00106661 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/08:00001275

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The activation of adult endogenous neural stem cells by neurodegenerative process within the striatum in an animal model of Huntington's disease

  • Original language description

    We have described the compartmentalization of the SEZ in relation to the intensity and manner of reaction of neurogenic niche to the neurodegenerative process within the striatum. Particularly we documented that astrocyte-like cells in the adult SEZ, during their extensive proliferation, retain some features of embryonic stem cells, including the reexpression of vimentin intermediate filaments which contributes to the suggestion that they are derivatives of radial glia.

  • Czech name

    Aktivace adultních endogenních neurálních kmenových buněk neurodegenerativním procesem ve striatu u experimentálního modelu Huntingtonovy choroby

  • Czech description

    Popsali jsme kompartmentalizaci SEV podle intenzity a způsobu reakce neurogenního niché na neurodegenerativní proces ve striatu. Zejména jsme prokázali, že astrocytům podobné buňky v dospělé SEV si, během své extenzivní proliferace, podržují některé znaky embryonálních kmenových buněk, včetně reexprese intermediálního filamenta vimentinu, což přispívá k předpokladu, že jsou deriváty radiální glie.

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Progress in stem cell aplications

  • ISBN

    978-1-60456-316-0

  • Number of pages of the result

    29

  • Pages from-to

  • Number of pages of the book

    435

  • Publisher name

    Nova Science Publishers

  • Place of publication

    New York

  • UT code for WoS chapter