Atorvastatin has hypolipidemic and anti-inflammatory effects in apoE/LDL receptor-double-knockout mice

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F08%3A00106846" target="_blank" >RIV/00216208:11150/08:00106846 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11160/08:00109205 RIV/00179906:_____/08:00001126
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Atorvastatin has hypolipidemic and anti-inflammatory effects in apoE/LDL receptor-double-knockout mice
Original language description
We demonstrated here for the first time strong hypolipidemic and anti-inflammatory effects of atorvastatin in apoE/LDLR-deficient mice. Thus, we propose that apoE/LDLR-deficient mice might be a good animal model for the study of statin effects on potential novel markers involved in atherogenesis and for the testing of potential combination treatment of new hypolipidemic substances with statins.
Czech name
Atorvastatin má hypolipidemický a protizánětlivý efekt u apoE/LDL receptir - double knockout myši
Czech description
V práci je poprvé popsán silný hypolipidemický protizánětlivý efekt atorvastatinu u apoE/LDL receptor-double-knockout myši.

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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