Effectiveness of antipsychotics in first-episode schizophrenia and schizophreniform disorder on response and remission: An open randomized clinical trial (EUFEST)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F09%3A00208854" target="_blank" >RIV/00216208:11150/09:00208854 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effectiveness of antipsychotics in first-episode schizophrenia and schizophreniform disorder on response and remission: An open randomized clinical trial (EUFEST)

Original language description

We compared the effectiveness of low doses of haloperidol and regular doses of second generation antipsychotics (SGAs) on >/=50% response measured with the Positive and Negative Syndrome Scale.and remission. In an open randomized clinical trial 498 unselected first-episode patients with schizophrenia were assigned to haloperidol, amisulpride, olanzapine, quetiapine, or ziprasidone. Within 12 months, the proportions of patients with >/=50% response were 37% for haloperidol, 67% for amisulpride, 67% for olanzapine, 46% for quetiapine, and 56% for ziprasidone. Within 12 months, the proportion of patients in remission was also the lowest in those treated with haloperidol , if compared to the patients treated with second generation antipsychotics.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FL - Psychiatry, sexology

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Schizophrenia Research

ISSN

0920-9964

e-ISSN

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Volume of the periodical

115

Issue of the periodical within the volume

2-3

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

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UT code for WoS article

000272423500001

EID of the result in the Scopus database

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