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Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F09%3A00209017" target="_blank" >RIV/00216208:11150/09:00209017 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis

  • Original language description

    To assess the effect of denosumab (dose 60 mg s.c. once in 6 months for three years) on the fracture ris in postmenopausal women (n=7868) in a double blind, pacebo controlled, randomized clinical trial. Denosumab decreased the risk of new fractures at the spine (by 68%), hip fractures (by 40%), non-vertebral fractures (by 20%). The safety profile of denosumab was very good, comparable to placebo.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FG - Paediatrics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    New England Journal of Medicine

  • ISSN

    0028-4793

  • e-ISSN

  • Volume of the periodical

    361

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000269081200004

  • EID of the result in the Scopus database