Up-regulation of renal Mdr1 and Mrp 2 transporters during amiodarone pretreatment in rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10001708" target="_blank" >RIV/00216208:11150/10:10001708 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11160/10:00300604 RIV/00179906:_____/10:10001708
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Up-regulation of renal Mdr1 and Mrp 2 transporters during amiodarone pretreatment in rats
Original language description
The aim of this study was to investigate the influence of amiodarone pretreatment on the main multidrug transporting proteins, Mdr1 and Mrp2, in the liver and kidney. Our results indicate that repeated administration of amiodarone to rats is associated with significant increase in hepatic and renal expression of Mdr1 and Mrp2 transporters.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/OC09072" target="_blank" >OC09072: Modulation of TNF-alpha and IL-1 activity as the treatment option during endotoxin induced organ injury.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pharmacological Research
ISSN
1043-6618
e-ISSN
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Volume of the periodical
61
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
000275009700005
EID of the result in the Scopus database
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