All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Amniotic fluid alpha-fetoprotein microheterogeneity in the prenatal diagnosis of congenital disorders of glycosylation type Ia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10051465" target="_blank" >RIV/00216208:11150/10:10051465 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/10:10051465

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    Amniotic fluid alpha-fetoprotein microheterogeneity in the prenatal diagnosis of congenital disorders of glycosylation type Ia

  • Original language description

    Congenital disorders of glycosylation (CDG) are a group of clinically and biochemically diverse defects. The current screening methods (based on analysis of transferrin),which are used postnatally for the most frequent types, are however not suitable forprenatal diagnosis. The aim of the study was to investigate whether alterations in the microheterogeneity of alpha-fetoprotein in amniotic fluid would provide more reliable results. Isoelectric focusing with direct immunofixation and silver staining wasused for analyses. A difference in the relative proportion of individual alpha-fetoprotein bands (particularly increase of band II density) was found in a case where CDG has been diagnosed postnatally, and in two other samples from pregnancies which resulted in termination, without further examination. Verification of our results in another laboratory with the exclusion of several potentially pertinent variables is advisable.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FG - Paediatrics

  • OECD FORD branch

    —

Result continuities

  • Project

    —

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Chemistry and Laboratory Medicine

  • ISSN

    1434-6621

  • e-ISSN

    —

  • Volume of the periodical

    48

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    5

  • Pages from-to

    —

  • UT code for WoS article

    000283183300015

  • EID of the result in the Scopus database

    —

Similar results(10)

Assessment of human chorionic gonadotrophin and alpha-1-fetoprotein by IMMULITE and SEVAPHARMA kits in maternal serum of pregnant women in the first trimesterTransferrin mutations at the glycosylation site complicate diagnosis of congenital disorders of glycosylation type IPregnancy-associated plasma protein A (PAPP-A) in the first trimester.