The effect of chronic iron losses on liver regeneration in male and female rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10072332" target="_blank" >RIV/00216208:11150/10:10072332 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/10:10072332
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The effect of chronic iron losses on liver regeneration in male and female rats
Original language description
We studied the effect of iron deficiency on liver regeneration and innate immunity - respiratory burst of PMN. Wistar rats, males (M) and females (F) had sham withdrawals or males (M-w) and females (F-w) had nine blood withdrawals every week. All rats were sacrificed in 10th week after 67% hepatectomy (PH). We determined blood cell count, respiratory burst (RB), serum prohepcidin, estradiol, iron, iron binding capacity (TIBC) and liver iron stores. Both genders with blood withdrawals had early beginningof liver regeneration after PH. The preconditioning (withdrawals) leads to increase in iron turnover and stores following best reactivity of PMN, rapid decrease in serum prohepcidin, and early initiation of liver regeneration, mainly in females. Femaleshave higher iron turnover, liver iron stores more easily mobilized for blood losses, because next gravidity physiologically begin immediately after birth.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, CzechoSK
ISSN
1213-8118
e-ISSN
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Volume of the periodical
154
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
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UT code for WoS article
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EID of the result in the Scopus database
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