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Expression of urokinase plasminogen activator receptor on monocytes and granulocytes is modulated by cardiac surgery

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F11%3A10080375" target="_blank" >RIV/00216208:11150/11:10080375 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/11:10080375

  • Result on the web

    <a href="http://search.proquest.com/docview/858144469" target="_blank" >http://search.proquest.com/docview/858144469</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1177/0267659110389845" target="_blank" >10.1177/0267659110389845</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Expression of urokinase plasminogen activator receptor on monocytes and granulocytes is modulated by cardiac surgery

  • Original language description

    Aims: Coronary artery bypass grafting (CABG) is linked to the induction of the blood coagulation/fibrinolysis cascade, which is an integral component of inflammation induced by cardiac surgery. We followed the modulation of urokinase plasminogen activator receptor uPAR (CD87) separately for monocytes and granulocytes in blood of cardiac surgery patients. Methods: Expression of uPAR, analyzed as Median Fluorescence Intensity (MFI), on blood monocytes and granulocytes was determined by flow cytometry. Changes in uPAR expression in patients undergoing CABG using standard cardiopulmonary bypass ("on-pump") were compared to the changes in uPAR expression in patients undergoing CABG using mini-invasive cardiopulmonary bypass ("mini on-pump"). Conclusion: uPAR expression on granulocytes and monocytes is significantly modulated by cardiac surgery.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FN - Epidemiology, infection diseases and clinical immunology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Perfusion

  • ISSN

    0267-6591

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    115-121

  • UT code for WoS article

    000289081900007

  • EID of the result in the Scopus database