Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F11%3A10081782" target="_blank" >RIV/00216208:11150/11:10081782 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/11:10081782

Result on the web

<a href="http://www.nature.com/hr/journal/v34/n1/full/hr2010183a.html" target="_blank" >http://www.nature.com/hr/journal/v34/n1/full/hr2010183a.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/hr.2010.183" target="_blank" >10.1038/hr.2010.183</a>

Result language

angličtina

Original language name

Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy

Original language description

Difficult-to-control arterial hypertension is a common medical problem that may result from severe hypertensive disease or from poor adherence to the recommended medical treatment. The use of serum levels of prescribed antihypertensive drugs to evaluatethe adherence in individuals with difficult-to-control arterial hypertension was descibed. Serum drug levels (SDLs) were evaluated by liquid chromatography with mass spectrometry. Eighty-four patients who presented with uncontrolled blood pressure despite the recommended combination of at least three antihypertensives were enrolled in the study. In 55 (65.5%) patients, non-adherence was diagnosed. Our data suggest that an assessment of SDLs might be helpful before an extensive evaluation is initiated for difficult-to-control hypertension.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Hypertension Research

ISSN

0916-9636

e-ISSN

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Volume of the periodical

34

Issue of the periodical within the volume

1

Country of publishing house

JP - JAPAN

Number of pages

4

Pages from-to

87-90

UT code for WoS article

000285919100018

EID of the result in the Scopus database

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