The neurodegenerative process in a neurotoxic rat model and in patients with Huntington's disease: Histopathological parallels and differences

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F11%3A10082489" target="_blank" >RIV/00216208:11150/11:10082489 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/11:10082489
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0065128110001406" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0065128110001406</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.acthis.2010.11.007" target="_blank" >10.1016/j.acthis.2010.11.007</a>

Result language
angličtina
Original language name
The neurodegenerative process in a neurotoxic rat model and in patients with Huntington's disease: Histopathological parallels and differences
Original language description
This study indicates that significant parallels may be drawn between morphological findings gained from brain autopsies of Huntington's diseased (HD) patients and quolinic acid-lesioned rat brains (the most frequent animal model of HD), particularly in relation to the progression of the neuronal degeneration and rarefaction of neuropil resulting in severe striatal atrophy. Conversely, the development and character of reactive astrogliosis is principally conditioned by the severity (intensity) of striatal neurodegenerative process.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
—

Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)