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Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F11%3A10106326" target="_blank" >RIV/00216208:11150/11:10106326 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/11:10106326

  • Result on the web

    <a href="http://www.bmj.sk/2011/11206-10.pdf" target="_blank" >http://www.bmj.sk/2011/11206-10.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Tamoxifen/Norfloxacin interaction leading to QT interval prolongation in a female patient with extracranial meningioma

  • Original language description

    The autors report on a case of tamoxifen/norfloxacin interaction leading to QT interval prolongation in an 83-year-old female patient with extracranial meningioma treated with radiation and hormonal therapy (with Tamoxifen). This case report highlights the potential risk of tamoxifen causing depression of electrical impulse in sinoatrial node, leading to symptomatic sinus bradycardia with prolonged QT interval. At the same time it indicates the need to be on the look out for drug interactions (in our case between tamoxifen and norfloxacin), as well as to be aware of other drugs possibly inducing QT interval prolongation)

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Bratislavske Lekarske Listy

  • ISSN

    0006-9248

  • e-ISSN

  • Volume of the periodical

    112

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    2

  • Pages from-to

    353-354

  • UT code for WoS article

    000291378700010

  • EID of the result in the Scopus database