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The Effect of Mud-Bath Therapy on Bone Status in Rats During Adjuvant Subchronic Arthritis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F12%3A10130777" target="_blank" >RIV/00216208:11150/12:10130777 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Effect of Mud-Bath Therapy on Bone Status in Rats During Adjuvant Subchronic Arthritis

  • Original language description

    We studied influence of mud-bath on bone status in male Wistar rats with subchronic arthritis. Arthritis was induced by 2 subplantar injections of Freund's adjuvans with heat-killed Streptoccocus pyogenes. Groups: intact (int) on chippings; (con) arthritis on chippings; (san38) arthritis on hot sand; (mu38) arthritis on hot mud; (mu21) arthritis on mild mud. Bone mineral density (BMD, g/cm2) was measured by dual energy X-ray absorptiometry and femurs were tested biomechanically. Bone markers osteocalcin, PINP and CTX were analysed in bone. The hot bath appears indifferent in relation to osteoporosis, while cold mud-bath shows good effect on bone metabolism. The cold mud-baths help to reduce arthritic inflammation and pain and thereby lead to higher mobility with positive consequence on bone. BMD of right femur decreased vs. left in san38 (p=0.030) and mu38. Fracture load of right/left femur (N) decreased in experimental groups, significantly in san38. Fracture threshold of neck decreas

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Kralove

  • ISSN

    1211-4286

  • e-ISSN

  • Volume of the periodical

    55

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    5

  • Pages from-to

    133-137

  • UT code for WoS article

  • EID of the result in the Scopus database