Prothrombotic changes due to an increase in thyroid hormone levels

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10293568" target="_blank" >RIV/00216208:11150/15:10293568 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/15:10293568

Result on the web

<a href="http://dx.doi.org/10.1530/EJE-14-0801" target="_blank" >http://dx.doi.org/10.1530/EJE-14-0801</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1530/EJE-14-0801" target="_blank" >10.1530/EJE-14-0801</a>

Result language

angličtina

Original language name

Prothrombotic changes due to an increase in thyroid hormone levels

Original language description

Objective With increasing free thyroxine levels, a gradually rising risk of venous thromboembolism has been described in case-control studies. However, reports on the influence of thyroid hormones on haemostasis, while suggesting a hypercoagulable statein thyrotoxicosis, have often been inconclusive. The present study evaluates multiple markers of haemostasis and fibrinolysis in a paired design, making it more sensitive to changes in thyroid hormone levels. Design We analysed multiple variables in patients who shifted from severe hypothyroidism to mild hyperthyroidism during thyroid cancer treatment. Those with possible residual disease were excluded. Methods Ninety patients following total thyroidectomy were tested on two occasions: (a) before radioiodine remnant ablation and (b) 6 weeks later, on levothyroxine suppression treatment, and the results were compared using the Wilcoxon test for paired data. Results During levothyroxine treatment, significant increases (all p<0.001) in fi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

<a href="/en/project/NT13535" target="_blank" >NT13535: The relationship of thyroid hormones to haemostasis and haemocoagulation in thyroid cancer patients</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Endocrinology

ISSN

0804-4643

e-ISSN

—

Volume of the periodical

172

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

537-542

UT code for WoS article

000354626400009

EID of the result in the Scopus database

2-s2.0-84929511579