Safety of Early Carotid Endarterectomy after Intravenous Thrombolysis in Acute Ischemic Stroke
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10365685" target="_blank" >RIV/00216208:11150/17:10365685 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/17:10365685
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0890509616311487?via%3Dihub" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0890509616311487?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.avsg.2017.03.195" target="_blank" >10.1016/j.avsg.2017.03.195</a>
Alternative languages
Result language
angličtina
Original language name
Safety of Early Carotid Endarterectomy after Intravenous Thrombolysis in Acute Ischemic Stroke
Original language description
Background: The timing of carotid endarterectomy (CEA) after intravenous thrombolysis (IVT) is still a controversial issue. The aim of this study was to assess the safety of early carotid interventions in patients treated with thrombolysis for acute ischemic stroke. Material and methods: A retrospective analysis was performed using prospectively collected data from consecutive patients who underwent CEA for symptomatic internal carotid artery stenosis within 14 days after the index neurological event during the period from January 2013 to July 2016. Patients who had undergone IVT before CEA were identified. The primary outcome measures were any stroke and death rate at 30 days, symptomatic intracerebral hemorrhage and surgical site bleeding requiring intervention. Results: A total of 93 patients were included for the final analysis. Among these, 13 (14.0%) patients had undergone IVT prior to CEA while 80 (86.0%) patients had CEA only. The median time interval between IVT and CEA was 2 days (range 0-13). A subgroup of six patients underwent CEA within 24 hours of administration of IVT. The 30 days combined stroke and death rate was 7.7% (1 of 13) among patients undergoing IVT prior to CEA and 5.0% (4 of 80) among those undergoing CEA only (p=0.690). In the IVT group, there were no cerebral hemorrhages or significant surgical site bleeding events requiring reintervention. Conclusions: Our experience indicates that CEA performed early after IVT for acute ischemic stroke, aiming not only to reduce the risk of stroke recurrence, but also to achieve neurological improvement by reperfusion of the ischemic penumbra, may be safe and can lead to favorable outcomes.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30212 - Surgery
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Annals of Vascular Surgery
ISSN
0890-5096
e-ISSN
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Volume of the periodical
44
Issue of the periodical within the volume
May
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
353-360
UT code for WoS article
000415241300042
EID of the result in the Scopus database
2-s2.0-85020121525