Revisiting the refeeding syndrome: Results of a systematic review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10365985" target="_blank" >RIV/00216208:11150/17:10365985 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/17:10365985
Result on the web
<a href="http://dx.doi.org/10.1016/j.nut.2016.05.016" target="_blank" >http://dx.doi.org/10.1016/j.nut.2016.05.016</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.nut.2016.05.016" target="_blank" >10.1016/j.nut.2016.05.016</a>
Alternative languages
Result language
angličtina
Original language name
Revisiting the refeeding syndrome: Results of a systematic review
Original language description
Objective: Although described > 70 y ago, the refeeding syndrome (RFS) remains understudied with lack of standardized definition and treatment recommendations. The aim of this systematic review was to gather evidence regarding standardized definition, incidence rate and time course of occurrence, association with adverse clinical outcomes, risk factors, and therapeutic strategies to prevent or treat this condition. Methods: We searched MEDLINE and EMBASE for interventional and observational clinical trials focusing on RFS, excluding case reports and reviews. We extracted data based on a predefined case report form and assessed bias. Results: Of 2207 potential abstracts, 45 records with a total of 6608 patients were included (3 interventional trials, 16 studies focusing on anorexic patients). Definitions for RFS were highly heterogenous with most studies relying on blood electrolyte disturbances only and others also including clinical symptoms. Incidence rates varied between 0% and 80%, depending on the definition and patient population studied. Occurrence was mostly within the first 72 h of start of nutritional therapy. Most of the risk factors were in accordance with National Institute for Health and Care Excellence guidelines, with older age and enteral feeding being additional factors. There was no strong evidence regarding association of RFS and adverse outcomes, as well as regarding preventive measures and treatment algorithms. Conclusion: This systematic review focusing on RFS found consensus regarding risk factors and timing of occurrence, but wide variations regarding definition, reported incidence rates, preventive measures and treatment recommendations. Further research to fill this gap is urgently needed.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30308 - Nutrition, Dietetics
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nutrition
ISSN
0899-9007
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
March
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
151-160
UT code for WoS article
000397697900024
EID of the result in the Scopus database
2-s2.0-85009450713