Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10366356" target="_blank" >RIV/00216208:11150/17:10366356 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/17:00099904 RIV/65269705:_____/17:00068016 RIV/00179906:_____/17:10366356
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0189394" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0189394</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0189394" target="_blank" >10.1371/journal.pone.0189394</a>

Result language
angličtina
Original language name
Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes
Original language description
The main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by pre-term prelabor rupture of membranes (PPROM) and the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). The second aim was to test WBC diagnostic indices with respect to the presence of MIAC and/or IAI. Four hundred and seventy-nine women with singleton pregnancies complicated by PPROM, between February 2012 and June 2017, were included in this study. Maternal blood and amniotic fluid samples were collected at the time of admission. Maternal WBC count was assessed. Women with MIAC or IAI had higher WBC counts than those without (with MIAC: median, 12.8 x 10(9) /L vs. without MIAC: median, 11.9 x 10(9) /L; p = 0.0006; with IAI: median, 13.7 x 10(9) /L vs. without IAI: median, 11.9 x 10(9)/L; p < 0.0001). The maternal WBC count at the time of admission showed poor diagnostic indices for the identification of the presence of both MIAC and IAI.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology

Project
<a href="/en/project/NV16-28587A" target="_blank" >NV16-28587A: Non-invasive detection of intraamniotic infection based on identification of dominant bacteria in cervical fluid</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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