Comparison of two long-term gestagen regimens in the management of recurrent vulvovaginal candidiasis: A pilot study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10366358" target="_blank" >RIV/00216208:11150/17:10366358 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/17:10366358 RIV/00179906:_____/17:10366358

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1111/myc.12593" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/myc.12593</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/myc.12593" target="_blank" >10.1111/myc.12593</a>

Result language

angličtina

Original language name

Comparison of two long-term gestagen regimens in the management of recurrent vulvovaginal candidiasis: A pilot study

Original language description

Vulvovaginal candidiasis (VVC) is a hormonal-dependent infection but in contrast to sporadic VVC, therapy of recurrent vulvovaginal candidiasis (RVVC) is still unsolved. Long-term administration of medroxyprogesterone acetate was evaluated for the management of RVVC. Overall, 20 patients were treated with Depo-Provera; 14 patients were treated with Provera. Gestagen therapy was evaluated based on visual analogue scale (VAS), the frequency of attacks, the side effects of gestagens and the consumption of antifungals. There was a reduced symptomatology in both of the groups and substantial reduction in antifungal drug consumption during the second year of gestagen use. Twenty-four patients (70.6%) evaluated their condition regarding the vulvovaginal area as improvement (VAS decrease of 3-5 points). Five patients (14.7%) mentioned minimal or no improvement. Further, a number of antifungal drug-treated episodes dropped dramatically during the study period. Both regimes provided similar results, but five patients from the Depo-Provera group had to withdraw from gestagen therapy. Gestagen supplementation ameliorated the quality of life for the majority of patients with RVVC and suggested a potential role in the management of this syndrome, even if beneficial effect was evident after longer application, and some patients met with side effects that led to an interruption of therapy.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30216 - Dermatology and venereal diseases

Project

<a href="/en/project/NV15-29225A" target="_blank" >NV15-29225A: Study of vaginal microbiota and its relationship to recurrent vulvovaginal discomfort</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mycoses

ISSN

0933-7407

e-ISSN

—

Volume of the periodical

60

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

260-265

UT code for WoS article

000395433700007

EID of the result in the Scopus database

2-s2.0-85014511198