Pentraxin 3 and other inflammatory biomarkers related to atrial fibrillation in cardiac surgery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10368322" target="_blank" >RIV/00216208:11150/17:10368322 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/17:10368322
Result on the web
<a href="http://dx.doi.org/10.1177/0267659116679248" target="_blank" >http://dx.doi.org/10.1177/0267659116679248</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/0267659116679248" target="_blank" >10.1177/0267659116679248</a>
Alternative languages
Result language
angličtina
Original language name
Pentraxin 3 and other inflammatory biomarkers related to atrial fibrillation in cardiac surgery
Original language description
Objectives: The aim was to evaluate the association between perioperative inflammatory biomarkers and atrial fibrillation (AF) in cardiac surgical patients. Methods: Forty-two patients undergoing cardiac surgery were divided into three groups according to the occurrence of AF: Group A (n = 22) - patients with no AF, Group B (n = 11) - patients with new onset AF postoperatively and Group C (n = 9) - patients with preoperative history of atrial fibrillation. The serum levels of PTX3, CRP, TLR2, IL-8, IL-18, sFas, MMP-7 and MMP-8 were measured at the following time points: before surgery, immediately and 6 h after surgery and on the 1(st), 3(rd) and 7(th) postoperative days (POD). Results: Serum levels of PTX3 showed a significant difference between Groups A and C on the 3(rd) POD (p<0.05) and on the 7(th) POD (p<0.0001). IL-8 levels were different between Groups A and C immediately after surgery (p<0.05), 6 hours after surgery (p<0.05) and on the 3(rd) POD (p<0.05). There was a difference between Groups B and C on the 1(st) POD in IL-8 levels (p<0.05). The sFas levels differed between Groups A and C on the 3(rd) POD (p<0.01) and the 7(th) POD (p<0.05). There was also a difference on the 7(th) POD (p<0.05) between the Groups B and C. No significant differences between the groups was seen for other biomarkers. Conclusion: This study demonstrates significantly different dynamics of PTX3, IL-8 and sFas levels after cardiac surgery in relation to AF.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Perfusion
ISSN
0267-6591
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
269-278
UT code for WoS article
000400121000003
EID of the result in the Scopus database
2-s2.0-85018253936