Late preterm prelabor rupture of fetal membranes: fetal inflammatory response and neonatal outcome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F18%3A10370436" target="_blank" >RIV/00216208:11150/18:10370436 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/18:10370436

Result on the web

<a href="http://dx.doi.org/10.1038/pr.2017.300" target="_blank" >http://dx.doi.org/10.1038/pr.2017.300</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/pr.2017.300" target="_blank" >10.1038/pr.2017.300</a>

Result language

angličtina

Original language name

Late preterm prelabor rupture of fetal membranes: fetal inflammatory response and neonatal outcome

Original language description

To characterize the influence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI) on the intensity of the fetal inflammatory response and the association between the presence of the fetal inflammatory response syndrome (FIRS) and short-term neonatal morbidity in the preterm prelabor rupture of membranes (PPROM) between the gestational ages of 34 and 37 weeks. One hundred and fifty-nine women were included in the study. The umbilical cord blood interleukin (IL)-6 concentrations were determined using enzyme-linked immunosorbent assay kits. FIRS was defined based on the umbilical cord blood IL-6 concentration and the presence of funisitis and/or chorionic plate vasculitis. Women with both MIAC and IAI had the highest median umbilical cord blood IL-6 concentrations and highest rates of FIRS. Women with FIRS had the higher rates of early-onset sepsis and intraventricular hemorrhage grades I and II when FIRS was characterized based on the umbilical cord blood IL-6 concentrations and the histopathological findings. The presence of both MIAC and IAI was associated with a higher fetal inflammatory response and a higher rate of FIRS. Different aspects of short-term neonatal morbidity were related to FIRS when defined by umbilical cord blood IL-6 concentrations and the histopathology of the placenta.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30214 - Obstetrics and gynaecology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pediatric Research

ISSN

0031-3998

e-ISSN

—

Volume of the periodical

83

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

630-637

UT code for WoS article

000430304300012

EID of the result in the Scopus database

2-s2.0-85045574840