Lactobacilli-dominated cervical microbiota in women with preterm prelabor rupture of membranes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F20%3A10407148" target="_blank" >RIV/00216208:11150/20:10407148 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/20:00116019 RIV/65269705:_____/20:00072716 RIV/00179906:_____/20:10407148 RIV/00843989:_____/20:E0108431
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hyKbiT4QYV" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hyKbiT4QYV</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41390-019-0692-1" target="_blank" >10.1038/s41390-019-0692-1</a>
Alternative languages
Result language
angličtina
Original language name
Lactobacilli-dominated cervical microbiota in women with preterm prelabor rupture of membranes
Original language description
Background: To determine the association between microbial invasion of the amniotic cavity (MIAC) and the presence of Lactobacillus crispatus- or Lactobacillus iners-dominated cervical microbiota in pregnancies with preterm prelabor rupture of membrane. Next, to assess the relationship between the presence of L. crispatus- or L. iners-dominated cervical microbiota and short-term neonatal morbidity. Method: A total of 311 women were included. Cervical samples were obtained using a Dacron polyester swab and amniotic fluid samples were obtained by transabdominal amniocentesis. Bacterial DNA, L. crispatus, and L. iners in the cervical samples were assessed by PCR. Cervical microbiota was assigned as L. crispatus- or L. iners-dominated when the relative abundance of L. crispatus or L. iners was >=50% of the whole cervical microbiota, respectively. Results: Women with MIAC showed a lower rate of L. crispatus-dominated cervical microbiota (21% vs. 39%; p = 0.003) than those without MIAC. Lactobacillus crispatus-dominated cervical microbiota was associated with a lower rate of early-onset sepsis (0% vs. 5%; p = 0.02). Conclusions: The presence of L. crispatus-dominated cervical microbiota in women with preterm prelabor rupture of membrane was associated with a lower risk of intra-amniotic complications and subsequent development of early-onset sepsis of newborns.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology
Result continuities
Project
<a href="/en/project/NV16-28587A" target="_blank" >NV16-28587A: Non-invasive detection of intraamniotic infection based on identification of dominant bacteria in cervical fluid</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pediatric Research
ISSN
0031-3998
e-ISSN
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Volume of the periodical
87
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
952-960
UT code for WoS article
000525281400027
EID of the result in the Scopus database
2-s2.0-85076155990