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Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)- A Helicobacter-opposite point

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10428631" target="_blank" >RIV/00216208:11150/21:10428631 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/21:10428631

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cuV4jOD0fw" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cuV4jOD0fw</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bpg.2021.101728" target="_blank" >10.1016/j.bpg.2021.101728</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)- A Helicobacter-opposite point

  • Original language description

    Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is a rare familial gastric cancer syndrome with an autosomal dominant pattern of inheritance. It is characterised by fundic gland polyposis of the gastric body and is associated with a significant risk of gastric adenocarcinoma. Unlike sporadic gastric cancer, Helicobacter pylori is usually absent in patients with GAPPS. This opposite-point finding has so far not been fully clarified. Prophylactic total gastrectomy is indicated in all cases of GAPPS with fundic gland polyposis and the presence of any dysplasia. If no dysplasia is found at histology, prophylactic gastrectomy is suggested at between 30 and 35 years of age, or at five years earlier than the age at which the youngest family member developed gastric cancer. Different phenotypes of GAPPS demand an individual approach to particular family members. (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30219 - Gastroenterology and hepatology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Best Practice and Research in Clinical Gastroenterology

  • ISSN

    1521-6918

  • e-ISSN

  • Volume of the periodical

    50-51

  • Issue of the periodical within the volume

    SI

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    12

  • Pages from-to

    101728

  • UT code for WoS article

    000648871800006

  • EID of the result in the Scopus database

    2-s2.0-85101709838