Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)- A Helicobacter-opposite point
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10428631" target="_blank" >RIV/00216208:11150/21:10428631 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/21:10428631
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cuV4jOD0fw" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cuV4jOD0fw</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bpg.2021.101728" target="_blank" >10.1016/j.bpg.2021.101728</a>
Alternative languages
Result language
angličtina
Original language name
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)- A Helicobacter-opposite point
Original language description
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is a rare familial gastric cancer syndrome with an autosomal dominant pattern of inheritance. It is characterised by fundic gland polyposis of the gastric body and is associated with a significant risk of gastric adenocarcinoma. Unlike sporadic gastric cancer, Helicobacter pylori is usually absent in patients with GAPPS. This opposite-point finding has so far not been fully clarified. Prophylactic total gastrectomy is indicated in all cases of GAPPS with fundic gland polyposis and the presence of any dysplasia. If no dysplasia is found at histology, prophylactic gastrectomy is suggested at between 30 and 35 years of age, or at five years earlier than the age at which the youngest family member developed gastric cancer. Different phenotypes of GAPPS demand an individual approach to particular family members. (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30219 - Gastroenterology and hepatology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Best Practice and Research in Clinical Gastroenterology
ISSN
1521-6918
e-ISSN
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Volume of the periodical
50-51
Issue of the periodical within the volume
SI
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
101728
UT code for WoS article
000648871800006
EID of the result in the Scopus database
2-s2.0-85101709838