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SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10435237" target="_blank" >RIV/00216208:11150/21:10435237 - isvavai.cz</a>

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=jSkqE7zBrU" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=jSkqE7zBrU</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1177/20499361211048572" target="_blank" >10.1177/20499361211048572</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID

  • Original language description

    Over 10% of COVID-19 convalescents report post-COVID-19 complications, namely, &apos;long COVID&apos; or &apos;post-COVID syndrome,&apos; including a number of neuro-psychiatric symptoms. The pathophysiology of COVID-19 in the central nervous system is poorly understood but may represent post-COVID injury, ongoing sterile maladaptive inflammation, or SARS-CoV-2 persistence. We describe a long COVID patient with SARS-CoV-2 RNA in the cerebrospinal fluid, which seems important, specifically due to recent reports of gray matter volume loss in COVID-19 patients. Further studies of SARS-CoV2 RNA, markers of inflammation, and neuronal damage in the CSF of patients with long COVID would be useful and should address whether the CNS can serve as a reservoir of SARS-CoV-2, clarify the pathway by which COVID-19 contributes to CNS dysfunction, and how best to therapeutically address it.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Therapeutic Advances in Infectious Disease

  • ISSN

    2049-9361

  • e-ISSN

  • Volume of the periodical

    8

  • Issue of the periodical within the volume

    OCT

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    20499361211048572

  • UT code for WoS article

    000706351600001

  • EID of the result in the Scopus database

    2-s2.0-85116601966