SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10435237" target="_blank" >RIV/00216208:11150/21:10435237 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=jSkqE7zBrU" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=jSkqE7zBrU</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/20499361211048572" target="_blank" >10.1177/20499361211048572</a>
Alternative languages
Result language
angličtina
Original language name
SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID
Original language description
Over 10% of COVID-19 convalescents report post-COVID-19 complications, namely, 'long COVID' or 'post-COVID syndrome,' including a number of neuro-psychiatric symptoms. The pathophysiology of COVID-19 in the central nervous system is poorly understood but may represent post-COVID injury, ongoing sterile maladaptive inflammation, or SARS-CoV-2 persistence. We describe a long COVID patient with SARS-CoV-2 RNA in the cerebrospinal fluid, which seems important, specifically due to recent reports of gray matter volume loss in COVID-19 patients. Further studies of SARS-CoV2 RNA, markers of inflammation, and neuronal damage in the CSF of patients with long COVID would be useful and should address whether the CNS can serve as a reservoir of SARS-CoV-2, clarify the pathway by which COVID-19 contributes to CNS dysfunction, and how best to therapeutically address it.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Therapeutic Advances in Infectious Disease
ISSN
2049-9361
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
OCT
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
20499361211048572
UT code for WoS article
000706351600001
EID of the result in the Scopus database
2-s2.0-85116601966