Multiplex Protein Biomarker Profiling in Patients with Familial Hypercholesterolemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10436180" target="_blank" >RIV/00216208:11150/21:10436180 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/21:00081855 RIV/00216208:11110/21:10436180 RIV/00179906:_____/21:10436180 RIV/00216208:11310/21:10436180
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=vEBi7aSfgZ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=vEBi7aSfgZ</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/genes12101599" target="_blank" >10.3390/genes12101599</a>
Alternative languages
Result language
angličtina
Original language name
Multiplex Protein Biomarker Profiling in Patients with Familial Hypercholesterolemia
Original language description
Familial hypercholesterolemia, is an autosomal dominant disorder caused by mutations in the LDLR, APOB, PCSK9, and APOE genes and is characterized by high plasma levels of total and low-density lipoprotein (LDL) cholesterol. Our study aimed to analyze the influences of two different therapies on a wide spectrum of plasma protein biomarkers of cardiovascular diseases. Plasma from FH patients under hypolipidemic therapy and patients under combined long-term LDL apheresis/hypolipidemic therapy were analyzed in our study. We measured a profile of 184 cardiovascular diesase associated proteins using a proximity extension assay.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Genes
ISSN
2073-4425
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
10
Country of publishing house
CH - SWITZERLAND
Number of pages
14
Pages from-to
1599
UT code for WoS article
000769343200001
EID of the result in the Scopus database
2-s2.0-85117762603