Prognostic factors affecting the outcome after allogeneic haematopoietic stem cell transplantation for myelodysplastic syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F21%3A10442135" target="_blank" >RIV/00216208:11150/21:10442135 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/21:10442135

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KD5IKEtRx5" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=KD5IKEtRx5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.lrr.2021.100274" target="_blank" >10.1016/j.lrr.2021.100274</a>

Result language

angličtina

Original language name

Prognostic factors affecting the outcome after allogeneic haematopoietic stem cell transplantation for myelodysplastic syndrome

Original language description

In the present study, we retrospectively analysed the results of HSCT in 47 consecutive patients with MDS diagnosed at our department between 2002 and 2019, with a focus on possible predictive factors influencing overall survival (OS), the development of relapse, infections, and the occurrence of graft versus host disease (GvHD). In a univariate analysis, the pre-transplantation value of blasts in the marrow &lt; 5% (p = 0.006), the revised International Prognostic Scoring System (IPSS-R) (p = 0.041), and karyotype (p = 0.009) were predictive of OS. Neither the elevation of serum ferritin (&gt; 1000 ug/ml) nor increased C-reactive protein (CRP) (&gt; 5 mg/l) was associated with shorter OS. In contrast, elevated serum lactate dehydrogenase (LDH) (&gt; 213 U/l) was associated with shorter OS (p = 0.04).

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30205 - Hematology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Leukemia Research Reports

ISSN

2213-0489

e-ISSN

—

Volume of the periodical

16

Issue of the periodical within the volume

JAN

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

100274

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85117843917