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Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F22%3A10453920" target="_blank" >RIV/00216208:11150/22:10453920 - isvavai.cz</a>

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5crI7W9N.0" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=5crI7W9N.0</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1167/tvst.11.12.7" target="_blank" >10.1167/tvst.11.12.7</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of Dioptric Blur on Pattern-Reversal and Motion-Onset VEPs as Used in Clinical Research

  • Original language description

    Purpose: To describe the effect of dioptric blur on visual evoked potentials (VEPs) induced by motion onset (MO-VEPs).Methods: The effect of dioptric blur up to 4 D on MO-VEPs was tested on 12 subjects using central, peripheral, and full-field stimulation with a low-contrast structure of concentric circles with spatial frequency &lt;1 c/°. The results were compared to VEPs evoked by 15ʹ and 60ʹ checkerboard pattern-reversal (PR-VEPs). The relationship between peak time and interpeak amplitude of the dominant components was related to the level of dioptric blur using linear regression.Results: The MO-VEPs did not show a significant peak prolongation (P &gt; 0.28) or amplitude attenuation (P &gt; 0.14) with the blur, whereas for the PR-VEPs we observed a significant decrease in amplitude (P &lt; 0.001) and increase in peak time (P &lt; 0.001) for both checkerboard sizes.Conclusions: For MO-VEPs induced by radial motion of low contrast and low spatial frequency pattern, the change in retinal blur does not affect the peak time or the interpeak amplitude of the dominant N2 component.Translational Relevance: The resistance to retinal blur that we demonstrated for MO-VEP provides a diagnostic opportunity to test the integrity of the visual system and reveal a retrobulbar impairment even in uncorrected refractive errors.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30207 - Ophthalmology

Result continuities

  • Project

    <a href="/en/project/NV18-06-00484" target="_blank" >NV18-06-00484: Improving the quality of life in patients with stable maculopathy by implanting intraocular macula lenses and modulating visual plasticity by transcranial electrical stimulation</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Translational Vision Science &amp; Technology

  • ISSN

    2164-2591

  • e-ISSN

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    7

  • UT code for WoS article

    000956649200001

  • EID of the result in the Scopus database

    2-s2.0-85143545889