Bronchospasm after timolol administration
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F25%3A10499266" target="_blank" >RIV/00216208:11150/25:10499266 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hh0YZltdnX" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hh0YZltdnX</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5114/ait/200233" target="_blank" >10.5114/ait/200233</a>
Alternative languages
Result language
angličtina
Original language name
Bronchospasm after timolol administration
Original language description
Timolol is a non-selective b-adrenergic receptor-blocking agent. It is topically administered in patients suffering from open-angle glaucoma or ocular hypertension. Among this patient population, timolol is usually prescribed alongside prostaglandin analogues. The prevalence of glaucoma increases with age. Most patients treated with timolol for glaucoma are of advanced age and may have various comorbidities such as diabetes mellitus, chronic obstructive pulmonary disease (COPD), and arterial hypertension. Notably, in the female population with COPD, the prevalence of open-angle glaucoma is significantly higher than in the general population. Timolol's systemic absorption and central nervous system penetration can lead to several side effects, including bradycardia, bronchospasm, increased fatigue, or confusion. We would like to present two cases wheretimolol administration resulted in severe, life-threatening bronchospasm, followed by hypoxic cardiac arrest in patients with COPD and asthma.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30223 - Anaesthesiology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anaesthesiology Intensive Therapy
ISSN
1642-5758
e-ISSN
1731-2531
Volume of the periodical
57
Issue of the periodical within the volume
1
Country of publishing house
PL - POLAND
Number of pages
2
Pages from-to
"e130"-"e131"
UT code for WoS article
001521457400002
EID of the result in the Scopus database
2-s2.0-105010161601